Homocysteine tests measure the level of homocysteine, a protein normally found in small amounts in all cells of the body, in the blood. The test requires drawing blood and sending it to a laboratory for analysis. Some studies suggest a relationship between too much homocysteine in the blood and higher risk for heart disease, stroke, and blood vessel disease. Other studies suggest, but have not proven, that homocysteine causes fatty deposits, damage to the inner lining of arteries, and blood clots. However, a direct cause and effect have not been found between too much homocysteine and these conditions. Your diet and heredity influence the homocysteine protein levels in your blood. Folic acid and other B vitamins found in your diet help to break down and decrease the amount of homocysteine in your body.

• According to the American Heart Association, there is not enough evidence to show who would and who would not benefit from lowering homocysteine levels.
• According to the American Heart Association, everyone -including people at high risk for cardiovascular disease - should get enough folic acid and vitamins B6 and B12 in their diet.
• No professional organization has made any official recommendation as to the dose of folic acid and other B vitamins needed for the treatment of high blood homocysteine levels.

Will I live longer if I have this procedure?

No, there is no evidence that testing your homocysteine level will lengthen your life.

Will the testing for homocysteine level improve my quality of life?

No, there is no evidence that testing your homocysteine level will improve the quality of your life.

Does the testing for homocysteine level make my symptoms better?

No, there is no evidence that testing your homocysteine level will make your symptoms better.

How safe is this for me?

There is very little risk from having a blood sample taken from a vein to determine homocysteine level. It would be necessary for you to go without eating for 12 hours before the blood is taken. You may develop a bruise at the puncture site, and in rare cases the vein may become inflamed. If you have a bleeding problem or take blood-thinning medication, you should tell your doctor before the blood sample is drawn.

Researchers are investigating the value of homocysteine levels to try to learn if too much homocysteine may in some way cause the risk of cardiovascular disease. No conclusions have yet been reached.

Alternative treatments include:

• Eat a healthy diet rich in citrus fruits, tomatoes, green leafy vegetables, whole grains, fortified bread and fat-free or low-fat dairy products.
• Maintain a healthy lifestyle by exercising and eating a balanced diet.
• Maintain control of other heart disease risk factors such as smoking, high blood cholesterol, high blood pressure, diabetes, and obesity.

The cost for homocysteine testing can range from $50 to $110 for each test. The cost could vary depending upon the laboratory doing the test and the area of the country where you have the test done.

The cost may or may not be covered by insurance.

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